Just like drugs for humans, they come with side effects and you have to weight out the benefit vs. the risks. Its been 2yrs of no Atopica. We finally got to take his cone off and start to enjoy walks again fully and his paws turned back to their original colorwhite! Drug interactions Hydroxyzine magnifies the effects of sedatives and inhibits the effect of stimulatory medications. I took him to my vet who then sent me to Emergency. I know my Dog, . http://www.fda.gov/AnimalVeterinary/SafetyHealth/ProductSafetyInformation/ucm055369.htm, http://definitions.uslegal.com/s/slander/, http://creative.advanstar.com/mkdv/2011/mkdv_vetbenchmarks_email0811/images/VBMZ300_preview.pdf, http://news.zoetis.com/press-release/investors/zoetis-reports-fourth-quarter-and-full-year-2014-results#sthash.hYHWSMPk.dpuf, http://www.2ndchance.info/Apoquel-Comments.htm, http://www.dogsnaturallymagazine.com/wouldnt-give-dog-new-allergy-drug/. Gave this med to my 9 year old Rat Terrier.. now she is dead. After a few months the vet recommended Apoquel, we never thought to ask about side effects. Even if a dog does not show immediate symptoms that are visually seen, I feel that internal immune system suppression and damage are occurring unseen and potentially will cause issues in the future that some dogs will not be able to be recovered from. For the past month or so he just wasnt right; lethargic, increased ear infections and two weeks ago while chasing a ball it looked as though a linebacker took the legs out from under him, but only on his right side. Hydroxyzine for dogs is available in tablets, capsules, syrup, and injectables. Yes, you can give your dog Apoquel and Zyrtec together. My dog (a 12 year old shepherd mix) is about a month or so in on this medication, which has miraculously stopped most, if not all of her itching (which she has had her whole life, is indoors, and was previously on prednisone for). That is when I found all the other comments with the other symptoms she had. Apoquel is safe to use in dogs one year and older. Thanks again Dr. Jones. Denise. our 17 year old cairn terrier has been on Apoquel for 4 mos. Its incredible how this drug is not off the market!! Common names: chlorpheniramine, chlorpheniramine maleate. When I woke up this morning, I could see that his condition had taken a turn for the worse. Anyone else having these issues? It comes in tablet form and is given daily, providing relief for 24 hours. Making her sick. Efficacy of dimetinden and hydroxyzine/chlorpheniramine in atopic dogs: a randomised, controlled, double-blinded trial, What To Do When Your Puppy Pees In The House, How Do You Potty Train A 4 Month Old Puppy, What To Do When Your Puppy Hates Leash Walking, How To Stop My Cockapoo Puppy From Biting, an increase of pruritus (if the drug is given in high doses), cardiovascular problems (particularly in the case of an overdose), US National Library of Medicine: MedlinePlus , Book: Church D.B., Small Animal Clinical Pharmacology Elsevier Health Sciences, 2008. Because most of the placebo dogs dropped out, they really couldnt compare the groups. But just a few days later she was falling and pacing and panting. Puppy was briefly having loose stool and some vomiting cleared up w/Flagyl- metronizone. Auggie needs this medicine this medicine needs to be cheaper and safer for his liver and kidneys. Most veterinarians say no because both drugs can cause drowsiness. And now hes scratching like crazy again. However, he also developed skin growths right around that time and they will not go away. The omega 3 dose I suggest is 1000 mg per 10lbs daily- this works out to giving 1 tablespoon of flax per 50lbs daily to your dog. I got him at six weeks old, so I can say I know him better than anyone. I am sure making a good living is a consideration. Then the swelling of the legs, so bad that it looked like he had huge donuts under his skin around his ankles. My 15 year old Cairn developed environmental allergies when she moved to CT from FL. DrugBank Accession Number. Apoquel can be used along with: antibiotics antifungals anti-arthritis drugs The vet took blood and urine. The first 30 days there seemed to be no side effects, his appetite was good and it stopped the itching immediately upon the first dose he received. Apoquel wont work for my pin , her itching decreased, but never stopped, and it has side effects. For the prescriptions !!! Any one with me? The dogs doctors dont feel Apoquel is the cause, but they are going about the practice of medicine to make a determination, not jumping on your band wagon. Or pups under 12 months old. No more seizures so do yourself a favor and stay very far away from this medication. So hard to do and they dont even care as long as they make their money at $200 a bottle take it vantage of court animals and people. Histamines are compounds in the body which are responsible for the symptoms we experience when we are allergic to something. If the wind blows the wrong way she starts breaking out. No episodes of stumbling. Instead of continuing to be a veterinarian, helping those innocent animals, and even keeping them from going to other veterinarians that may not explain the risks with medications, you quit, to sell supplements and offer a one sided view. Can Apoquel be used with other medications? Other than some itching she has always been healthy. After two trips to the vet, then being referred to a specialists, we learned his liver enzymes were off the charts. We gave it a try because her itchiness was causing almost a seizure like problem. of the development of severe pyoderma (after day 19) and one dog withdrew because of the My husband took him to the Vet for his routine checkup on June 16th, he got a clean bill of health as usual. Sadly, with the infections appearing after only a month on the drug, I felt in order to save her life, I had to take her off Apoquel, as I could only guess at the havoc she was going through internally from having her immune system suppressed. She is otherwise fine during the day this just seems to happen at night. If you are looking for a quick and easy way to help your dogs allergies, I suggest you try my supplement, Dr Jones Ultimate Canine Health Formula. At the onset of all this she started behaving very depressed. We cannot imagine how horrible the situation for all would have been if we began this drug and our little buddy suffered any ill effects. A lot of dog owners are asking how much Apoquel their dog can take. But I love my dogs and if this is what happens with using Apoquel. He is a different dog entirely now that his life isnt consumed by itchiness and chewing and scratching. 8 3/4 yr old unknown mix (black & tan head, white with black spotted body & pink skin) to the vet after almost 8 years. I never, ever, leave my dogs side when they are a procedure until they are out, but this one was brutal. Im not one to complain but, I feel compelled to share our nightmarish experience with this new anti-itching drug called Apoquel. Does Apoquel interact with any medications? Your email address will not be published. How long can my dog use Apoquel? There are a lot of factors to consider when trying to determine which is better for dogs Benadryl or Zyrtec. As I write this my 4 month old puppy is in ICU getting I.V. Maybe more so because now I know that he had no tumor, nothing anywhere, it was the APOQUEL. No more for my precious girl! I have put her on a probiotic to see if that gives her some relief. keep me up all night and day biting,scratiching licking she is a happy dog. I find that hydroxyzine work best for my girl but that requires an Rx. Go ahead with apoquel. Apparently either your company representative, the veterinarians or both are not being made aware that this serious adverse event is occurring in dogs exposed to Apoquel with long term use. Im Apoquel researching online today because my dog developed scary adverse effects. Vet said it was not the Apoquil. She almost immediately stopped itching and I was delighted. I am now convinced its the apoquel. Gets up on the Saturday and couldnt find him. I have also found that if we keep his paws shaved or very short that helps tremendously. We give her oatmeal baths and it dont help. 5.Essential Fatty Acid supplements. Hydroxyzine belongs to a family of drugs called antihistamines. The treatment can be very effective. Just yesterday his lab panel showed elevated liver enzymes and he was transferred to a 24 hour emergency hospital. She cant even find her toys unless I put them in her mouth. We all need to do our part to get this drug off the market. This happened three times over a few weeks, he also learned how to open the door to the garage and was scratching at the window trying to escape. Is there such a movement in the veterinary world? This generation of antihistamine also crosses the blood-brain barrier and acts on the histamine receptors in the central nervous system. Im always sceptical of new drugs and wish I had just said no to Apoquel. Just like an earlier person wrote my dog was howling during the seizure. But then, she became actually fearful of people she formerly would jump up and down to give them kisses. Hydroxyzine (brand names: Atarax, Vistaril, Masmoran, Multipax) is an antihistamine used to treat allergic and itchy conditions or as a sedative/tranquilizer. Seemingly startled that it happened. Im wondering if anyone has had luck with a very low dose achieving less itching with less side effects? I think he had an overgrowth of yeast, so in february I tried nzymes.com. Died in hospital where we had to carry her. His nose is cold and his behavior is normal, but we are very worried. I WOULD NOT recommend giving Apoquel to your pet!! Bit worried my E.R. My dog has also been getting large pyoderma lesions on his skin for about a year now but we were told this was part of his worsening allergic problem as he aged.I now know this was the drug preventing him from fighting off skin infections. There are a few things to bear in mind when giving your dog antihistamines: We hope this has helped to answer your question. We saw great results by the 2nd day and by now his gland would have flared up and has not, we were all getting to sleep at night! Dogs are able to take hydroxyzine. It was generally well tolerated, with the . Today we was at the vets, my Westie mix bison was given Apoquel 5.6grm and I gave him one today,after reading all your comments. We rescued our Min Pin Buddy 8 yrs ago. Antihistamines are most often taken to relieve the symptoms of allergic reactions, such as itchiness. No vet should use this drug!!! I am so pleased to have Apoquel that keeps him happy and well. I am giving my own allergic dog an oatmeal shampoo weekly. We adopted this puppy from the Animal Defense League 2/16/2016. Please everyone try Natural pet! Antihistamines can also be used to treat anxiety, and to calm patients before general anesthesia and surgery. Not like her at all. I just feel I needed to share these issues just in case anyone else has a pet that is suffering these same or similar symptoms. We went back inside and for the rest of the night she cried and stared off into space. Vet said to try him on Apoquel. Monitor your dog for any symptoms. In fact, antihistamines are quite often used to treat skin allergies in dogs. My German Shepherd started on Apoquel about five months ago. Bit worried about that. Apoquel side effects listed for dogs in the product insert include: vomiting, diarrhea, lethargy, anorexia, SQ or dermal masses (unspecified), decreased leukocytes, decreased globulins, and increased cholesterol and lipase. Have had my 20 month old westie on it for the last two weeks. After 1 month she was reduced to 1 in the morning. After an examination, they may deem it appropriate to prescribe an antihistamine as part of the treatment plan. Even when it was off the market, I had a doctor who had a source for me to continue getting the drug. Its all about the money! But it is not the only antihistamine that vets use. What are the side effects of hydroxyzine in dogs? Doctor said he also showed signs of neurological damage and he was bleeding from his rectum. I felt terrible because she was still itching during this battle with cancer so I kept her on the Apoquel. The last couple of days she has been trembling and has also gone aggressive to our older dog (she has NEVER done this before). Do not use Apoquel in dogs less than 12 months of age or those with serious infections. Hydroxyzine for dogs is a canine antihistamine. They treated him with holistic drugs. Indianna veterinary dermatologist, Dr. Stacey L. Silva, DACVD, explains that while the active ingredient in Apoquel, oclacitinib, inhibits the production of histamines, its still unknown how the drug works to decrease inflammation and the itch associated with allergies. During the initial first 14 day period her itching just vanished BUT I noticed her having one or two weird wobbles, not thinking much of it I continued with the Apoquel. Antihistamines can also be used to treat anxiety, and to calm patients before general anesthesia and surgery, found that 54% of dogs with atopic dermatitis that had been given antihistamines to treat the condition responded favorably, your dog may be displaying signs of anxiety because of discomfort, Hydroxyzine hydrochloride is the most common treatment for pruritus in dogs, Best Dog Food For Seniors With Sensitive Stomachs, Best Dog Food for Small Dogs with Sensitive Stomachs, Hydrogen Peroxide For Dogs Vomiting, Ears, Wounds, Other Issues. I took my 58# However, we always recommend that you speak to your vet before starting any new medication, just to be sure. After the allergy tests I gave him Natural Balance Sweet Potato and Fish, which he doesnt eat much so I add other things to it. If you want to help call: Roger 586-343-9003 Also she was not falling down for no reason. Now we will take her to Neurologist. I was not told he could contract opportunistic fungal infections, but this is a huge risk for dogs who are on this drug. Of those 247 dogs, they removed 26 dogs from the study for one reason or another and 18 were euthanized. He is a cocker spaniel who is now just over 10 years old. I took her home and she was ok for a few days. I brought her home and gave her 1 dose of 16 mg around 4PM. so I went back to my regular vet I trusted who pit Ollie on ever increasing steroids to try to kill this yeast infection. So, does Apoquel stop itching? my newfie takes 1 1/2 tabs. Be very wary of any vet, or human doctor for that matter, that touts a medicine without side effects. He had not requested to go outside and potty in almost 20 hours. My chocolate lab has been on Apoquel for years now. Does zonisamide interact with my other drugs? My puppy is exhibiting the same bad side effects others mentioned in this post. Thanks to all for yoru comments. Im at the end of the road here in my hopes for Ollie to be healthy. Can any of these symptoms be reversed or are they permanent damage? The above mentioned worked but she also added Atopica for 3 5 months to sustain the gut so he wouldnt itch anymore. I cannot believe his Dr. gave a medicine that might cause gastro-intestinal problems and suppress the immune system to a puppy that has a weaken immune system from mange and had recent stool and vomiting issues. )mange that is non contagious. As always, you should talk to your veterinarian before starting your dog on any new medication, even if its something as seemingly innocuous as Benadryl or Zyrtec. The reports of the studies list everything that the animals in the studies had while in the study, but a causative relationship cannot be made, merely an association . This drug may stop your dogs itching, however creating long Apoquel scares me with with how quickly my frenchie started getting infections, instability, diarrhea and was still mildly itchy (probably from the yeast infections she was getting). doubted that Apoquel was the cause. Seems Im out $147 for a month supply. Can my dog take Apoquel and Zyrtec together? He is aware of the harmful side effects of prescription drugs and is trying to give us healthier alternatives for our loving pets. The dose of Apoquel tablets is 0.18-0.27 mg/lb (0.4-0.6 mg/kg). Went back to vet and they wanted her to go to specialist which she did this week.only wanted to run $2000.00 of allergies testbut vet didnt even put their hands on her.. Didnt think much of it until I watch her over the weekendOMG this baby was having a seizure !!!! It has been launched with much fanfarefrom Zoetis.. FDA Approves APOQUEL (oclacitinib tablet) to Control Itch and Inflammation in Allergic Dogs, Zoetis Offers a Targeted New Approach to Rapidly and Safely Stop the Cycle of Itch and Inflammation Associated with Allergic Skin Disease in Dogs. Every dog that suffers from allergies may respond . We stopped Apoquel today because Alk phos is very high on last two tests. It will cost me $1200.00 so far I dont have to spare but he will be O.K. Which is better for dogs Benadryl or Zyrtec? She has NEVER done this, she wont even puke on the floor she runs to her crate she is the most courteous dog when it comes to messing anything up. Its use in cats, dogs, ferrets, horses, and birds to treat itchiness is 'off label' or 'extra label'. What are the side effects of hydroxyzine in dogs? HOW LONG CAN MY DOG USE APOQUEL? The US Food and Drug Administration (FDA) has not placed any time restrictions on the use of APOQUEL. He will not walk againthey think the infection is in his spine now. I am so grateful to have her but feel bad as she has to take 570 pills every month plus liquid medication, mostly due to her size. APOQUEL Zyrtec, Claritin, and Benadryl are just some of the meds that both humans and dogs can take safely. We are scheduled to go see our great dermatologist again as soon a weather permits the drive. On February 15, 2018, Aries was back at the center with same issue and again a Rx issued for 70 Apoquel 5.4mg tabs with a charge of $138.60. Translating the above means that for the first 2 weeks of medication the most common side effects are gastro-intestinal ( vomiting/diarrhea), BUT after 2 weeks, there are measurable blood value changes. Like everyone else it helped make her more comfortable at first then increased eating and lethargy. It may be given with or without food, but giving it with food may reduce the chances of GI side effects. I believe some of the vets push it because it is expensive. I have had her since she was 6 mths old and she is now an old lady at 13. My 10 year old Maltese 10 pound has had intermittent allergy problems his entire life. When I took him to the vet, he had 106 degree temp (above 102.5 in dogs is a fever) and they couldnt figure out where the infection was. She has been on it for over six months now. Hes been to Cornell, and we have tried just about everything. She gave him different food and Hydroxizine, along with antinausea pills. We stopped this medication as soon as we learned that she never should have been prescribed this in the first place as she had a previous cancerous tumour and also that it should not be given to a dog with a serious infection. The answer is yes, your dog can take Apoquel and Hydroxyzine together. company and they said no connections. I am aware that in the pharmaceutical world when a medication becomes FDA approved, the company must conduct as post marketing surveillance program to detect any adverse events or idiosyncratic reactions that occur especially when the medication is being utilized in a much large patient population. All of the sudden it clicked. I took both of my dogs off of Apoquell on 01/02/17 and they are both functioning normally. (Answered 2023). He has intermittent hotspots and a rash. We tried everything for our dogs itchy skin, and finally agreed to try Apoquel, although I was concerned about side effects. She was only on med for 2 weeks, had a stroke and stopped breathing on the way to try and get her help. She never did the digging thing previously. I am still waiting for a call back. She died in my arms on the way to the vet.My Zoey is gone and I am heart broken. He has food allergy tests done several years ago and is allergic to rice, peas, carrots and several other things. And the drug company should be ashamed of there self. These growths developed quickly within two weeks and caused concern warranting removal and testing. As I write this I just want everyone to know.the drug may stop the itching as it did with my dog, but it allows the immune system to weaken and your dog wont be able to fight off the most basic thing: fungus. Hard to articulate, more a pet parents knowing. He had been on steroids and antibiotics previously. Our dog scratches till she has raw sores on her stomach underarms and other blood present), urinary tract infections, aggressive behavior, So I stopped Apoquel after 3 weeks and she was better the next day. Im just heartbroken and will have to live with this guilt the rest of my life. Cons: I am pretty sure her seizures are tied in with a build up of Apoquel but its impossible to be sure. Ive learned in my research today that this adverse effect is actually happening somewhat frequently, or rather, Ive found many reports from pet owners whos dogs had this reaction. Then came the seizure. Thats where the court issues come from. None of these worked brilliantly but they did have an effect on reducing some of his symptoms. Apoquel may increase the chances of developing serious infections, and may cause existing parasitic skin infestations or pre-existing cancers to get worse. Two days ago, I woke up in the morning and went to feed by dog and he could not walk or stand. She examined him and told me that he was having a reaction to the hydroxyzine so dont give any more to him. I dont trust drugs and I dont trust doctors, or car sales men, or lawyers for that matter. Question: Can My Dog Take Apoquel And Zyrtec Quick Answer: Can Dogs Take Zyrtec Hydroxyzine And Apoquel Together Question: Can Give Dogs Zyrtec Question: How Much Zyrtec Give Dog Is It Safe To Gove A Dog Zyrtec And Apoquel Can U Give Dogs Zyrtec Can Zyrtec Give Dogs Diarrhea Miscellaneous Travel Tips During Covid 2022 Tips for Bike tour in the USA Guilt the rest of my life five months ago, had a doctor who had can my dog take apoquel and hydroxyzine together who... Road here in my hopes for Ollie to be sure and chewing and scratching may! Briefly having loose stool and some vomiting cleared up w/Flagyl- metronizone to at. To answer your question do yourself a favor and stay very far away from medication... Take Apoquel and Zyrtec together that requires an Rx I would not recommend giving Apoquel to your!! It was off the market! we finally got can my dog take apoquel and hydroxyzine together take his cone off and start to enjoy again... 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